BRAI3N aims to develop new neuromodulation treatments by combining the common neurophysiological mechanisms of diseases, such as the 'thalamocortical dysrhythmia' (tinnitus, pain, Parkinson, depression, epilepsy) and the 'reward deficiency syndromes' (obesity, addiction, obsessive-compulsive disorder, ADHD, Autism, Tourette and other "tic" syndromes, personality disorders).

BRAI3N is a multidisciplinary and international collaboration between doctors from different disciplines, specialists in neuromodulation, (neuro) psychologists, audiologists, physiotherapists and neuroscientists. Internationally they work closely together with labs in Ireland (Trinity College Dublin), USA (University of Texas at Dallas), New Zealand (University of Otago) and South Korea (Seoul National University Bundang Hospital).

To complement each other, each partner focuses on a specific part of the joint scientific research. As a result, new scientific insights can be applied clinically and new clinical insights can also be scientifically tested. This way they can quickly apply new, scientifically founded treatment protocols.